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Drug Discovery Applications of High-Throughput Cytological Discovery Systems

High-content screening is a crucial technique in drug development, utilized both in the initial phases for identifying new candidate compounds and in later phases for assessing the pharmacological effects and safety of these candidates. This report highlights three applications using Yokogawa’s CellVoyager CV8000 and CQ1 high-content screening systems, paired with Yokogawa’s CellPathfinder analysis software, creating an integrated and user-friendly platform for drug discovery.

Featured Assays

  1. Hepatotoxicity Assay: Evaluating the effect of vitamin K on HepG2 cells.
  2. Cell Migration Assay: Investigating the impact of mitomycin C on cell migration.
  3. In Vivo Tumor Metastasis: Studying tumor metastasis using zebrafish models.

 

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